Chloe: Cystic Fibrosis and Living-Donor Lung-Lobe Transplant

The episode gives a concrete transplant case: Chloe has cystic fibrosis and needs a lung-lobe transplant from Yolanda, but donor fever and drug exposure complicate the plan.

Sam tells Chloe the surgery cannot happen as scheduled because Yolanda has a fever; Chloe worsens and needs ventilation; Yolanda later admits ecstasy use; the team proceeds to surgery after reassessing the risk.

For lung transplant, the recipient must be sick enough to need transplant but stable enough to survive surgery, and the donor must be medically safe and properly evaluated.

A real transplant team would review Chloe's cystic fibrosis severity, oxygenation, ventilator settings, infection status, cultures, imaging, heart-lung function, donor compatibility, Yolanda's fever workup, toxicology relevance, consent, and donor surgical risk.

Management would include stabilizing Chloe's breathing, infection assessment, transplant surgery planning, donor evaluation, anesthesia and ICU coordination, immunosuppression planning, infection prevention, and long-term follow-up.

The donor's drug use should be treated as a clinical safety and consent issue, not as a moral shortcut. Real transplant teams would evaluate specific risks before proceeding.